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The arachidonic acid metabolite 11β-ProstaglandinF2α controls intestinal epithelial healing: deficiency in patients with Crohn’s disease

In healthy gut enteric glial cells (EGC) are essential to intestinal epithelial barrier (IEB) functions. In Crohn’s Disease (CD), both EGC phenotype and IEB functions are altered, but putative involvement of EGC in CD pathogenesis remains unknown and study of human EGC are lacking. EGC isolated from...

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Detalles Bibliográficos
Autores principales: Coquenlorge, Sabrina, Van Landeghem, Laurianne, Jaulin, Julie, Cenac, Nicolas, Vergnolle, Nathalie, Duchalais, Emilie, Neunlist, Michel, Rolli-Derkinderen, Malvyne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853710/
https://www.ncbi.nlm.nih.gov/pubmed/27140063
http://dx.doi.org/10.1038/srep25203