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In vivo 3D measurement of moxifloxacin and gatifloxacin distributions in the mouse cornea using multiphoton microscopy
Moxifloxacin and gatifloxacin are fourth-generation fluoroquinolone antibiotics used in the clinic to prevent or treat ocular infections. Their pharmacokinetics in the cornea is usually measured from extracted ocular fluids or tissues, and in vivo direct measurement is difficult. In this study multi...
Autores principales: | Lee, Seunghun, Lee, Jun Ho, Park, Jin Hyoung, Yoon, Yeoreum, Chung, Wan Kyun, Tchah, Hungwon, Kim, Myoung Joon, Kim, Ki Hean |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853790/ https://www.ncbi.nlm.nih.gov/pubmed/27138688 http://dx.doi.org/10.1038/srep25339 |
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