Cargando…

Modulatory Effect of Betulinic Acid on the Genotoxicity Induced by Different Mutagens in V79 Cells

Betulinic acid (BA) is a pentacyclic triterpene that can be isolated from many medicinal plants around the world. The aim of this study was to evaluate the genotoxic potential of BA and its effect on the genotoxicity induced by different mutagens in V79 cells using the cytokinesis-block micronucleus...

Descripción completa

Detalles Bibliográficos
Autores principales:	Acésio, Nathália Oliveira, de Oliveira, Pollyanna Francielli, Mastrocola, Daiane Fernanda Pereira, Lima, Ildercílio Mota de Souza, Munari, Carla Carolina, Sato, Vânia Luiza Ferreira Lucatti, Souza, Andressa Aparecida Silva, Flauzino, Lúzio Gabriel Bocalon, Cunha, Wilson Roberto, Tavares, Denise Crispim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853943/ https://www.ncbi.nlm.nih.gov/pubmed/27195016 http://dx.doi.org/10.1155/2016/8942730

Ejemplares similares

Genotoxic and Chemopreventive Effects of Vochysia divergens Leaves (Pantanal, Brazil)
por: de Oliveira, Pollyanna Francielli, et al.
Publicado: (2018)

In Vivo Assessment of Genotoxic, Antigenotoxic and Anticarcinogenic Activities of Solanum lycocarpum Fruits Glycoalkaloidic Extract
por: Munari, Carla Carolina, et al.
Publicado: (2014)

Evaluation of a Propolis Water Extract Using a Reliable RP-HPLC Methodology and In Vitro and In Vivo Efficacy and Safety Characterisation
por: Rocha, Bruno Alves, et al.
Publicado: (2013)

Data in support of the mutagenic potential of the isoflavone irilone in cultured V79 cells
por: Scheffler, Anne, et al.
Publicado: (2015)

Genotoxicity and mutagenicity research in Quilombola communities
por: de Moraes Filho, Aroldo Vieira, et al.
Publicado: (2020)

Mutagenic and Genotoxic Effect of Hydroxyurea
por: Santos, Jean L., et al.
Publicado: (2011)

Mutagenicity and genotoxicity of ClearTaste
por: Soni, B.K., et al.
Publicado: (2018)

Genotoxicity and Mutagenicity of Inosine Pranobex
por: Tobólska, Sylwia, et al.
Publicado: (2018)

Comparative Studies of the (Anti) Mutagenicity of Baccharis dracunculifolia and Artepillin C by the Bacterial Reverse Mutation Test
por: Resende, Flávia Aparecida, et al.
Publicado: (2012)

Biological Activity and In Silico Study of 3-Modified Derivatives of Betulin and Betulinic Aldehyde
por: Bębenek, Ewa, et al.
Publicado: (2019)

Mutagenicity and antimutagenicity of (−)-hinokinin a trypanosomicidal compound measured by Salmonella microsome and comet assays
por: Resende, Flávia Aparecida, et al.
Publicado: (2012)

Anti-Inflammatory Activities of Betulinic Acid: A Review
por: Oliveira-Costa, José Fernando, et al.
Publicado: (2022)

Pesquisa em sepse pediátrica em países de baixa e média renda: superando desafios
por: de Souza, Daniela Carla, et al.
Publicado: (2021)

High cytotoxicity of betulin towards fish and murine fibroblasts: Is betulin safe for nonneoplastic cells?
por: Małaczewska, Joanna, et al.
Publicado: (2021)

Arrayed functional genetic screenings in pluripotency reprogramming and differentiation
por: Panepucci, Rodrigo Alexandre, et al.
Publicado: (2019)

Compounds used to produce cloned animals are genotoxic and mutagenic in mammalian assays in vitro and in vivo
por: Oliveira, R.J., et al.
Publicado: (2014)

Atypical presentation of cutaneous herpes simplex virus in a patient with chronic lymphocytic leukemia
por: Carneiro, Clívia Maria Moraes de Oliveira, et al.
Publicado: (2019)

Antileishmanial Activity of Semisynthetic Lupane Triterpenoids Betulin and Betulinic Acid Derivatives: Synergistic Effects with Miltefosine
por: Sousa, Maria C., et al.
Publicado: (2014)

Cutaneous sarcoidosis with livedo-like manifestation
por: Bittencourt, Maraya de Jesus Semblano, et al.
Publicado: (2019)

Cell-Free Production of Pentacyclic Triterpenoid Compound Betulinic Acid from Betulin by the Engineered Saccharomyces cerevisiae
por: Wu, Jianan, et al.
Publicado: (2017)

Evaluation of the mutagenicity and antimutagenicity of Ziziphus joazeiro Mart. bark in the micronucleus assay
por: Boriollo, Marcelo Fabiano Gomes, et al.
Publicado: (2014)

Enzymatic Hydrolysis of Rutin: Evaluation of Kinetic Parameters and Anti-Proliferative, Mutagenic and Anti-Mutagenic Effects
por: Sobreiro, Mariana Alves, et al.
Publicado: (2023)

Betulinic Acid for Cancer Treatment and Prevention
por: Fulda, Simone
Publicado: (2008)

Betulinic Acid Exerts Cytoprotective Activity on Zika Virus-Infected Neural Progenitor Cells
por: Cavalcante, Bruno R. R., et al.
Publicado: (2020)

Antimicrobial Potential of Betulinic Acid and Investigation of the Mechanism of Action against Nuclear and Metabolic Enzymes with Molecular Modeling
por: Rodrigues, Gabriela Cristina Soares, et al.
Publicado: (2023)

Genetic toxicology of phthalate esters: mutagenic and other genotoxic effects.
por: Douglas, G R, et al.
Publicado: (1986)

Recent Perspectives on the Relations between Fecal Mutagenicity, Genotoxicity, and Diet
por: Gratz, Silvia W., et al.
Publicado: (2011)

Genotoxicity and mutagenicity of Echinodorus macrophyllus (chapéu-de-couro) extracts
por: Vidal, Leonardo S., et al.
Publicado: (2010)

Crystal structure of glycidamide: the mutagenic and genotoxic metabolite of acrylamide
por: Hemgesberg, Melanie N., et al.
Publicado: (2016)

QSAR ligand dataset for modelling mutagenicity, genotoxicity, and rodent carcinogenicity
por: Guan, Davy, et al.
Publicado: (2018)

Antiproliferative, neurotoxic, genotoxic and mutagenic effects of toxic cyanobacterial extracts
por: Andeden, Enver Ersoy, et al.
Publicado: (2018)

Chemopreventive effect of Copaifera langsdorffii leaves hydroalcoholic extract on 1,2-dimethylhydrazine-induced DNA damage and preneoplastic lesions in rat colon
por: Senedese, Juliana Marques, et al.
Publicado: (2013)

Effects of indirubin and isatin on cell viability, mutagenicity, genotoxicity and BAX/ERCC1 gene expression
por: Fogaça, Manoela Viar, et al.
Publicado: (2017)

Antineoplastic Agents. 595. Structural Modifications of Betulin and the X-ray Crystal Structure of an Unusual Betulin Amine Dimer1
por: Pettit, George R., et al.
Publicado: (2014)

Modulatory Effects of Guarana (Paullinia cupana) on Adipogenesis
por: Lima, Natália da Silva, et al.
Publicado: (2017)

The Triterpenoid Betulin Protects against the Neuromuscular Effects of Bothrops jararacussu Snake Venom In Vivo
por: Ferraz, Miriéle Cristina, et al.
Publicado: (2015)

Genotoxic and mutagenic effects of polluted surface water in the midwestern region of Brazil using animal and plant bioassays
por: Dourado, Priscila Leocádia Rosa, et al.
Publicado: (2016)

Crystal structure of betulinic acid methanol monosolvate
por: Tang, Wei, et al.
Publicado: (2014)

Betulin Phosphonates; Synthesis, Structure, and Cytotoxic Activity
por: Chrobak, Elwira, et al.
Publicado: (2016)

Purity and Uncertainty Study of CRM Betulin by DSC
por: Zhang, Li, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_4545eqgj8lq1m3fosbnvvrhina