Cargando…
Sclerosing hemangioma: A diagnostic dilemma in fine needle aspiration cytology
Sclerosing hemangioma of the lung is a benign neoplasm with a widely debated histogenesis. It has a polymorphic histomorphology characterized by a biphasic cell population of “surface cells” and “round cells” arranged in four general patterns: Papillary, solid, angiomatous, and sclerotic. This varia...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854032/ https://www.ncbi.nlm.nih.gov/pubmed/27168758 http://dx.doi.org/10.4103/1742-6413.180783 |
_version_ | 1782430167625367552 |
---|---|
author | Zeng, Jennifer Zhou, Fang Wei, Xiao-Jun Kovacs, Sandor Simsir, Aylin Shi, Yan |
author_facet | Zeng, Jennifer Zhou, Fang Wei, Xiao-Jun Kovacs, Sandor Simsir, Aylin Shi, Yan |
author_sort | Zeng, Jennifer |
collection | PubMed |
description | Sclerosing hemangioma of the lung is a benign neoplasm with a widely debated histogenesis. It has a polymorphic histomorphology characterized by a biphasic cell population of “surface cells” and “round cells” arranged in four general patterns: Papillary, solid, angiomatous, and sclerotic. This variability in histomorphology makes it difficult to diagnose sclerosing hemangioma by fine needle aspiration (FNA). We present a case of sclerosing hemangioma diagnosed on FNA with immunohistochemistry performed on an accompanied cell block. The clinical presentation, cytomorphology, immunohistochemistry, and differential diagnoses are discussed. |
format | Online Article Text |
id | pubmed-4854032 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-48540322016-05-10 Sclerosing hemangioma: A diagnostic dilemma in fine needle aspiration cytology Zeng, Jennifer Zhou, Fang Wei, Xiao-Jun Kovacs, Sandor Simsir, Aylin Shi, Yan Cytojournal Case Report Sclerosing hemangioma of the lung is a benign neoplasm with a widely debated histogenesis. It has a polymorphic histomorphology characterized by a biphasic cell population of “surface cells” and “round cells” arranged in four general patterns: Papillary, solid, angiomatous, and sclerotic. This variability in histomorphology makes it difficult to diagnose sclerosing hemangioma by fine needle aspiration (FNA). We present a case of sclerosing hemangioma diagnosed on FNA with immunohistochemistry performed on an accompanied cell block. The clinical presentation, cytomorphology, immunohistochemistry, and differential diagnoses are discussed. Medknow Publications & Media Pvt Ltd 2016-04-20 /pmc/articles/PMC4854032/ /pubmed/27168758 http://dx.doi.org/10.4103/1742-6413.180783 Text en Copyright: © 2016 Zeng, et al.; Licensee Cytopathology Foundation Inc. http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Zeng, Jennifer Zhou, Fang Wei, Xiao-Jun Kovacs, Sandor Simsir, Aylin Shi, Yan Sclerosing hemangioma: A diagnostic dilemma in fine needle aspiration cytology |
title | Sclerosing hemangioma: A diagnostic dilemma in fine needle aspiration cytology |
title_full | Sclerosing hemangioma: A diagnostic dilemma in fine needle aspiration cytology |
title_fullStr | Sclerosing hemangioma: A diagnostic dilemma in fine needle aspiration cytology |
title_full_unstemmed | Sclerosing hemangioma: A diagnostic dilemma in fine needle aspiration cytology |
title_short | Sclerosing hemangioma: A diagnostic dilemma in fine needle aspiration cytology |
title_sort | sclerosing hemangioma: a diagnostic dilemma in fine needle aspiration cytology |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854032/ https://www.ncbi.nlm.nih.gov/pubmed/27168758 http://dx.doi.org/10.4103/1742-6413.180783 |
work_keys_str_mv | AT zengjennifer sclerosinghemangiomaadiagnosticdilemmainfineneedleaspirationcytology AT zhoufang sclerosinghemangiomaadiagnosticdilemmainfineneedleaspirationcytology AT weixiaojun sclerosinghemangiomaadiagnosticdilemmainfineneedleaspirationcytology AT kovacssandor sclerosinghemangiomaadiagnosticdilemmainfineneedleaspirationcytology AT simsiraylin sclerosinghemangiomaadiagnosticdilemmainfineneedleaspirationcytology AT shiyan sclerosinghemangiomaadiagnosticdilemmainfineneedleaspirationcytology |