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Sclerosing hemangioma: A diagnostic dilemma in fine needle aspiration cytology

Sclerosing hemangioma of the lung is a benign neoplasm with a widely debated histogenesis. It has a polymorphic histomorphology characterized by a biphasic cell population of “surface cells” and “round cells” arranged in four general patterns: Papillary, solid, angiomatous, and sclerotic. This varia...

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Autores principales: Zeng, Jennifer, Zhou, Fang, Wei, Xiao-Jun, Kovacs, Sandor, Simsir, Aylin, Shi, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854032/
https://www.ncbi.nlm.nih.gov/pubmed/27168758
http://dx.doi.org/10.4103/1742-6413.180783
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author Zeng, Jennifer
Zhou, Fang
Wei, Xiao-Jun
Kovacs, Sandor
Simsir, Aylin
Shi, Yan
author_facet Zeng, Jennifer
Zhou, Fang
Wei, Xiao-Jun
Kovacs, Sandor
Simsir, Aylin
Shi, Yan
author_sort Zeng, Jennifer
collection PubMed
description Sclerosing hemangioma of the lung is a benign neoplasm with a widely debated histogenesis. It has a polymorphic histomorphology characterized by a biphasic cell population of “surface cells” and “round cells” arranged in four general patterns: Papillary, solid, angiomatous, and sclerotic. This variability in histomorphology makes it difficult to diagnose sclerosing hemangioma by fine needle aspiration (FNA). We present a case of sclerosing hemangioma diagnosed on FNA with immunohistochemistry performed on an accompanied cell block. The clinical presentation, cytomorphology, immunohistochemistry, and differential diagnoses are discussed.
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spelling pubmed-48540322016-05-10 Sclerosing hemangioma: A diagnostic dilemma in fine needle aspiration cytology Zeng, Jennifer Zhou, Fang Wei, Xiao-Jun Kovacs, Sandor Simsir, Aylin Shi, Yan Cytojournal Case Report Sclerosing hemangioma of the lung is a benign neoplasm with a widely debated histogenesis. It has a polymorphic histomorphology characterized by a biphasic cell population of “surface cells” and “round cells” arranged in four general patterns: Papillary, solid, angiomatous, and sclerotic. This variability in histomorphology makes it difficult to diagnose sclerosing hemangioma by fine needle aspiration (FNA). We present a case of sclerosing hemangioma diagnosed on FNA with immunohistochemistry performed on an accompanied cell block. The clinical presentation, cytomorphology, immunohistochemistry, and differential diagnoses are discussed. Medknow Publications & Media Pvt Ltd 2016-04-20 /pmc/articles/PMC4854032/ /pubmed/27168758 http://dx.doi.org/10.4103/1742-6413.180783 Text en Copyright: © 2016 Zeng, et al.; Licensee Cytopathology Foundation Inc. http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Zeng, Jennifer
Zhou, Fang
Wei, Xiao-Jun
Kovacs, Sandor
Simsir, Aylin
Shi, Yan
Sclerosing hemangioma: A diagnostic dilemma in fine needle aspiration cytology
title Sclerosing hemangioma: A diagnostic dilemma in fine needle aspiration cytology
title_full Sclerosing hemangioma: A diagnostic dilemma in fine needle aspiration cytology
title_fullStr Sclerosing hemangioma: A diagnostic dilemma in fine needle aspiration cytology
title_full_unstemmed Sclerosing hemangioma: A diagnostic dilemma in fine needle aspiration cytology
title_short Sclerosing hemangioma: A diagnostic dilemma in fine needle aspiration cytology
title_sort sclerosing hemangioma: a diagnostic dilemma in fine needle aspiration cytology
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854032/
https://www.ncbi.nlm.nih.gov/pubmed/27168758
http://dx.doi.org/10.4103/1742-6413.180783
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