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Active immunization with GnRH-tandem-dimer peptide in young male rats reduces serum reproductive hormone concentrations, testicular development and spermatogenesis

GnRH sterilization vaccines have been developed for various practical and clinical reasons. However, conjugation of GnRH peptide to carrier protein has many drawbacks, hampering the further commercialization of GnRH vaccines. In this study, a new nonconjugated GnRH vaccine, D-Lys6-GnRH-tandem-dimer...

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Detalles Bibliográficos
Autores principales: Han, Xing-Fa, Li, Jun-Li, Zhou, Yu-Qin, Ren, Xiao-Hua, Liu, Gong-Cheng, Cao, Xiao-Han, Du, Xiao-Gang, Zeng, Xian-Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854110/
https://www.ncbi.nlm.nih.gov/pubmed/26208395
http://dx.doi.org/10.4103/1008-682X.156856