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Active immunization with GnRH-tandem-dimer peptide in young male rats reduces serum reproductive hormone concentrations, testicular development and spermatogenesis
GnRH sterilization vaccines have been developed for various practical and clinical reasons. However, conjugation of GnRH peptide to carrier protein has many drawbacks, hampering the further commercialization of GnRH vaccines. In this study, a new nonconjugated GnRH vaccine, D-Lys6-GnRH-tandem-dimer...
Autores principales: | Han, Xing-Fa, Li, Jun-Li, Zhou, Yu-Qin, Ren, Xiao-Hua, Liu, Gong-Cheng, Cao, Xiao-Han, Du, Xiao-Gang, Zeng, Xian-Yin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854110/ https://www.ncbi.nlm.nih.gov/pubmed/26208395 http://dx.doi.org/10.4103/1008-682X.156856 |
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