Cargando…
NRP1 function and targeting in neurovascular development and eye disease
Neuropilin 1 (NRP1) is expressed by neurons, blood vessels, immune cells and many other cell types in the mammalian body and binds a range of structurally and functionally diverse extracellular ligands to modulate organ development and function. In recent years, several types of mouse knockout model...
Autores principales: | Raimondi, Claudio, Brash, James T., Fantin, Alessandro, Ruhrberg, Christiana |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Pergamon
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854174/ https://www.ncbi.nlm.nih.gov/pubmed/26923176 http://dx.doi.org/10.1016/j.preteyeres.2016.02.003 |
Ejemplares similares
-
NRP1 Regulates CDC42 Activation to Promote Filopodia Formation in Endothelial Tip Cells
por: Fantin, Alessandro, et al.
Publicado: (2015) -
VEGF(189) binds NRP1 and is sufficient for VEGF/NRP1-dependent neuronal patterning in the developing brain
por: Tillo, Miguel, et al.
Publicado: (2015) -
VEGF165-induced vascular permeability requires NRP1 for ABL-mediated SRC family kinase activation
por: Fantin, Alessandro, et al.
Publicado: (2017) -
Neuropilin 1 (NRP1) hypomorphism combined with defective VEGF-A binding reveals novel roles for NRP1 in developmental and pathological angiogenesis
por: Fantin, Alessandro, et al.
Publicado: (2014) -
Evaluating Vascular Hyperpermeability-inducing Agents in the Skin with the Miles Assay
por: Brash, James T., et al.
Publicado: (2018)