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Immunostimulatory Activity of the Cytokine-Based Biologic, IRX-2, on Human Papillomavirus-Exposed Langerhans Cells

Langerhans cells (LCs) are the antigen-presenting cells of the epithelial layer and are responsible for initiating immune responses against skin and mucosa-invading viruses. Human papillomavirus (HPV)-mediated suppression of LC function is a crucial mechanism of HPV immune evasion, which can lead to...

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Detalles Bibliográficos
Autores principales: Da Silva, Diane M., Woodham, Andrew W., Naylor, Paul H., Egan, James E., Berinstein, Neil L., Kast, W. Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854212/
https://www.ncbi.nlm.nih.gov/pubmed/26653678
http://dx.doi.org/10.1089/jir.2015.0115