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Refinement of atomic models in high resolution EM reconstructions using Flex-EM and local assessment
As the resolutions of Three Dimensional Electron Microscopic reconstructions of biological macromolecules are being improved, there is a need for better fitting and refinement methods at high resolutions and robust approaches for model assessment. Flex-EM/MODELLER has been used for flexible fitting...
Autores principales: | Joseph, Agnel Praveen, Malhotra, Sony, Burnley, Tom, Wood, Chris, Clare, Daniel K., Winn, Martyn, Topf, Maya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854230/ https://www.ncbi.nlm.nih.gov/pubmed/26988127 http://dx.doi.org/10.1016/j.ymeth.2016.03.007 |
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