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GQ-16, a TZD-Derived Partial PPARγ Agonist, Induces the Expression of Thermogenesis-Related Genes in Brown Fat and Visceral White Fat and Decreases Visceral Adiposity in Obese and Hyperglycemic Mice

BACKGROUND: Beige adipocytes comprise a unique thermogenic cell type in the white adipose tissue (WAT) of rodents and humans, and play a critical role in energy homeostasis. In this scenario, recruitment of beige cells has been an important focus of interest for the development of novel therapeutic...

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Detalles Bibliográficos
Autores principales: Coelho, Michella S., de Lima, Caroline L., Royer, Carine, Silva, Janaina B., Oliveira, Fernanda C. B., Christ, Camila G., Pereira, Sidney A., Bao, Sonia N., Lima, Maria C. A., Pitta, Marina G. R., Pitta, Ivan R., Neves, Francisco A. R., Amato, Angélica A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854408/
https://www.ncbi.nlm.nih.gov/pubmed/27138164
http://dx.doi.org/10.1371/journal.pone.0154310