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GQ-16, a TZD-Derived Partial PPARγ Agonist, Induces the Expression of Thermogenesis-Related Genes in Brown Fat and Visceral White Fat and Decreases Visceral Adiposity in Obese and Hyperglycemic Mice
BACKGROUND: Beige adipocytes comprise a unique thermogenic cell type in the white adipose tissue (WAT) of rodents and humans, and play a critical role in energy homeostasis. In this scenario, recruitment of beige cells has been an important focus of interest for the development of novel therapeutic...
Autores principales: | Coelho, Michella S., de Lima, Caroline L., Royer, Carine, Silva, Janaina B., Oliveira, Fernanda C. B., Christ, Camila G., Pereira, Sidney A., Bao, Sonia N., Lima, Maria C. A., Pitta, Marina G. R., Pitta, Ivan R., Neves, Francisco A. R., Amato, Angélica A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854408/ https://www.ncbi.nlm.nih.gov/pubmed/27138164 http://dx.doi.org/10.1371/journal.pone.0154310 |
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