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Functional and Structural Mimicry of Cellular Protein Kinase A Anchoring Proteins by a Viral Oncoprotein

The oncoproteins of the small DNA tumor viruses interact with a plethora of cellular regulators to commandeer control of the infected cell. During infection, adenovirus E1A deregulates cAMP signalling and repurposes it for activation of viral gene expression. We show that E1A structurally and functi...

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Detalles Bibliográficos
Autores principales: King, Cason R., Cohen, Michael J., Fonseca, Gregory J., Dirk, Brennan S., Dikeakos, Jimmy D., Mymryk, Joe S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854477/
https://www.ncbi.nlm.nih.gov/pubmed/27137912
http://dx.doi.org/10.1371/journal.ppat.1005621