Low Protective Efficacy of the Current Japanese Encephalitis Vaccine against the Emerging Genotype 5 Japanese Encephalitis Virus

BACKGROUND: The current Japanese encephalitis (JE) vaccine derived from G3 JE virus (JEV) can induce protective immunity against G1–G4 JEV genotypes. However, protective efficacy against the emerging G5 genotype has not been reported. METHODS/PRINCIPAL FINDINGS: Using in vitro and in vivo tests, bio...

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Detalles Bibliográficos
Autores principales: Cao, Lei, Fu, Shihong, Gao, Xiaoyan, Li, Minghua, Cui, Shiheng, Li, Xiaolong, Cao, Yuxi, Lei, Wenwen, Lu, Zhi, He, Ying, Wang, Huanyu, Yan, Jinghua, Gao, George Fu, Liang, Guodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854478/
https://www.ncbi.nlm.nih.gov/pubmed/27139722
http://dx.doi.org/10.1371/journal.pntd.0004686

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