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Substrate Binding Mode and Molecular Basis of a Specificity Switch in Oxalate Decarboxylase
[Image: see text] Oxalate decarboxylase (OxDC) catalyzes the conversion of oxalate into formate and carbon dioxide in a remarkable reaction that requires manganese and dioxygen. Previous studies have shown that replacing an active-site loop segment Ser(161)-Glu(162)-Asn(163)-Ser(164) in the N-termin...
Autores principales: | Zhu, Wen, Easthon, Lindsey M., Reinhardt, Laurie A., Tu, Chingkuang, Cohen, Steven E., Silverman, David N., Allen, Karen N., Richards, Nigel G. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854488/ https://www.ncbi.nlm.nih.gov/pubmed/27014926 http://dx.doi.org/10.1021/acs.biochem.6b00043 |
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