Cargando…

Substrate Binding Mode and Molecular Basis of a Specificity Switch in Oxalate Decarboxylase

[Image: see text] Oxalate decarboxylase (OxDC) catalyzes the conversion of oxalate into formate and carbon dioxide in a remarkable reaction that requires manganese and dioxygen. Previous studies have shown that replacing an active-site loop segment Ser(161)-Glu(162)-Asn(163)-Ser(164) in the N-termin...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Wen, Easthon, Lindsey M., Reinhardt, Laurie A., Tu, Chingkuang, Cohen, Steven E., Silverman, David N., Allen, Karen N., Richards, Nigel G. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854488/
https://www.ncbi.nlm.nih.gov/pubmed/27014926
http://dx.doi.org/10.1021/acs.biochem.6b00043

Ejemplares similares