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Gankyrin has an antioxidative role through the feedback regulation of Nrf2 in hepatocellular carcinoma
Oxidative stress status has a key role in hepatocellular carcinoma (HCC) development and progression. Normally, reactive oxygen species (ROS) levels are tightly controlled by an inducible antioxidant program that responds to cellular stressors. How HCC cells respond to excessive oxidative stress rem...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854728/ https://www.ncbi.nlm.nih.gov/pubmed/27091842 http://dx.doi.org/10.1084/jem.20151208 |