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Immune activation of the host cell induces drug tolerance in Mycobacterium tuberculosis both in vitro and in vivo

Successful chemotherapy against Mycobacterium tuberculosis (Mtb) must eradicate the bacterium within the context of its host cell. However, our understanding of the impact of this environment on antimycobacterial drug action remains incomplete. Intriguingly, we find that Mtb in myeloid cells isolate...

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Detalles Bibliográficos
Autores principales:	Liu, Yancheng, Tan, Shumin, Huang, Lu, Abramovitch, Robert B., Rohde, Kyle H., Zimmerman, Matthew D., Chen, Chao, Dartois, Véronique, VanderVen, Brian C., Russell, David G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2016
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854729/ https://www.ncbi.nlm.nih.gov/pubmed/27114608 http://dx.doi.org/10.1084/jem.20151248

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