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NAIP proteins are required for cytosolic detection of specific bacterial ligands in vivo

NLRs (nucleotide-binding domain [NBD] leucine-rich repeat [LRR]–containing proteins) exhibit diverse functions in innate and adaptive immunity. NAIPs (NLR family, apoptosis inhibitory proteins) are NLRs that appear to function as cytosolic immunoreceptors for specific bacterial proteins, including f...

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Detalles Bibliográficos
Autores principales: Rauch, Isabella, Tenthorey, Jeannette L., Nichols, Randilea D., Al Moussawi, Khatoun, Kang, James J., Kang, Chulho, Kazmierczak, Barbara I., Vance, Russell E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854734/
https://www.ncbi.nlm.nih.gov/pubmed/27045008
http://dx.doi.org/10.1084/jem.20151809