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NAIP proteins are required for cytosolic detection of specific bacterial ligands in vivo
NLRs (nucleotide-binding domain [NBD] leucine-rich repeat [LRR]–containing proteins) exhibit diverse functions in innate and adaptive immunity. NAIPs (NLR family, apoptosis inhibitory proteins) are NLRs that appear to function as cytosolic immunoreceptors for specific bacterial proteins, including f...
Autores principales: | Rauch, Isabella, Tenthorey, Jeannette L., Nichols, Randilea D., Al Moussawi, Khatoun, Kang, James J., Kang, Chulho, Kazmierczak, Barbara I., Vance, Russell E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854734/ https://www.ncbi.nlm.nih.gov/pubmed/27045008 http://dx.doi.org/10.1084/jem.20151809 |
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