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Genetic functions of the NAIP family of inflammasome receptors for bacterial ligands in mice
Biochemical studies suggest that the NAIP family of NLR proteins are cytosolic innate receptors that directly recognize bacterial ligands and trigger NLRC4 inflammasome activation. In this study, we generated Naip5(−/−), Naip1(−/−), and Naip2(−/−) mice and showed that bone marrow macrophages derived...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854738/ https://www.ncbi.nlm.nih.gov/pubmed/27114610 http://dx.doi.org/10.1084/jem.20160006 |