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Phenotyping by magnetic resonance imaging nondestructively measures glomerular number and volume distribution in mice with and without nephron reduction

Reduced nephron mass is strongly linked to susceptibility to chronic renal and cardiovascular diseases. There are currently no tools to identify nephropenia in clinical or preclinical diagnostics. Such new methods could uncover novel mechanisms and therapies for chronic kidney disease (CKD) and reve...

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Detalles Bibliográficos
Autores principales: Baldelomar, Edwin J., Charlton, Jennifer R., Beeman, Scott C., Hann, Bradley D., Cullen-McEwen, Luise, Pearl, Valeria M., Bertram, John F., Wu, Teresa, Zhang, Min, Bennett, Kevin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854807/
https://www.ncbi.nlm.nih.gov/pubmed/26535998
http://dx.doi.org/10.1038/ki.2015.316