Rif1 and Exo1 regulate the genomic instability following telomere losses

Telomere attrition is linked to cancer, diabetes, cardiovascular disease and aging. This is because telomere losses trigger further genomic modifications, culminating with loss of cell function and malignant transformation. However, factors regulating the transition from cells with short telomeres,...

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Detalles Bibliográficos
Autores principales: Xue, Yuan, Marvin, Marcus E., Ivanova, Iglika G., Lydall, David, Louis, Edward J., Maringele, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854909/
https://www.ncbi.nlm.nih.gov/pubmed/27004475
http://dx.doi.org/10.1111/acel.12466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854909/
https://www.ncbi.nlm.nih.gov/pubmed/27004475
http://dx.doi.org/10.1111/acel.12466

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