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AGEs in human lens capsule promote the TGFβ2‐mediated EMT of lens epithelial cells: implications for age‐associated fibrosis

Proteins in basement membrane (BM) are long‐lived and accumulate chemical modifications during aging; advanced glycation endproduct (AGE) formation is one such modification. The human lens capsule is a BM secreted by lens epithelial cells. In this study, we have investigated the effect of aging and...

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Detalles Bibliográficos
Autores principales:	Raghavan, Cibin T., Smuda, Mareen, Smith, Andrew J. O., Howell, Scott, Smith, Dawn G., Singh, Annapurna, Gupta, Pankaj, Glomb, Marcus A., Wormstone, Ian Michael, Nagaraj, Ram H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854921/ https://www.ncbi.nlm.nih.gov/pubmed/26853893 http://dx.doi.org/10.1111/acel.12450

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