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Reduced DNA methylation patterning and transcriptional connectivity define human skin aging
Epigenetic changes represent an attractive mechanism for understanding the phenotypic changes associated with human aging. Age‐related changes in DNA methylation at the genome scale have been termed ‘epigenetic drift’, but the defining features of this phenomenon remain to be established. Human epid...
Autores principales: | Bormann, Felix, Rodríguez‐Paredes, Manuel, Hagemann, Sabine, Manchanda, Himanshu, Kristof, Boris, Gutekunst, Julian, Raddatz, Günter, Haas, Rainer, Terstegen, Lara, Wenck, Horst, Kaderali, Lars, Winnefeld, Marc, Lyko, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854925/ https://www.ncbi.nlm.nih.gov/pubmed/27004597 http://dx.doi.org/10.1111/acel.12470 |
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