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Extracorporeal Irradiation and Reimplantation with Total Hip Arthroplasty for Periacetabular Pelvic Resections: A Review of 9 Cases

We report the early results of nine patients with periacetabular malignancies treated with Enneking and Dunham type 2 resection and reconstruction using extracorporeally irradiated (ECI) tumour bone combined with total hip arthroplasty (THA). Diagnosis was chondrosarcoma in six patients, osteosarcom...

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Autores principales: Chan, Lester Wai Mon, Imanishi, Jungo, Ngan, Samuel Y., Chander, Sarat, Chu, Julie, Thorson, Renae, Pang, Grant, Choong, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854988/
https://www.ncbi.nlm.nih.gov/pubmed/27199613
http://dx.doi.org/10.1155/2016/2549616
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author Chan, Lester Wai Mon
Imanishi, Jungo
Ngan, Samuel Y.
Chander, Sarat
Chu, Julie
Thorson, Renae
Pang, Grant
Choong, Peter
author_facet Chan, Lester Wai Mon
Imanishi, Jungo
Ngan, Samuel Y.
Chander, Sarat
Chu, Julie
Thorson, Renae
Pang, Grant
Choong, Peter
author_sort Chan, Lester Wai Mon
collection PubMed
description We report the early results of nine patients with periacetabular malignancies treated with Enneking and Dunham type 2 resection and reconstruction using extracorporeally irradiated (ECI) tumour bone combined with total hip arthroplasty (THA). Diagnosis was chondrosarcoma in six patients, osteosarcoma in two patients, and metastatic renal cell carcinoma in one patient. All patients underwent surgical resection and the resected specimen was irradiated with 50 Gy in a single fraction before being prepared for reimplantation as a composite autograft. The mean follow-up was 21 months (range, 3–59). All patients were alive at latest follow-up. No local recurrence was observed. One patient serially developed three pulmonary metastases, all of which were resected. One experienced hip dislocation due to incorrect seating of an acetabular liner. This was successfully treated with revision of the liner with no further episodes of instability. There were no cases of deep infection or loss of graft. The average Musculoskeletal Tumor Society (MSTS) score was 75% (range, 57–87%). Type 2 pelvic reconstruction with ECI and THA has shown excellent early oncological and functional results in our series. Preservation of the gluteus maximus and hip abductors is important for joint stability and prevention of infection.
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spelling pubmed-48549882016-05-19 Extracorporeal Irradiation and Reimplantation with Total Hip Arthroplasty for Periacetabular Pelvic Resections: A Review of 9 Cases Chan, Lester Wai Mon Imanishi, Jungo Ngan, Samuel Y. Chander, Sarat Chu, Julie Thorson, Renae Pang, Grant Choong, Peter Sarcoma Clinical Study We report the early results of nine patients with periacetabular malignancies treated with Enneking and Dunham type 2 resection and reconstruction using extracorporeally irradiated (ECI) tumour bone combined with total hip arthroplasty (THA). Diagnosis was chondrosarcoma in six patients, osteosarcoma in two patients, and metastatic renal cell carcinoma in one patient. All patients underwent surgical resection and the resected specimen was irradiated with 50 Gy in a single fraction before being prepared for reimplantation as a composite autograft. The mean follow-up was 21 months (range, 3–59). All patients were alive at latest follow-up. No local recurrence was observed. One patient serially developed three pulmonary metastases, all of which were resected. One experienced hip dislocation due to incorrect seating of an acetabular liner. This was successfully treated with revision of the liner with no further episodes of instability. There were no cases of deep infection or loss of graft. The average Musculoskeletal Tumor Society (MSTS) score was 75% (range, 57–87%). Type 2 pelvic reconstruction with ECI and THA has shown excellent early oncological and functional results in our series. Preservation of the gluteus maximus and hip abductors is important for joint stability and prevention of infection. Hindawi Publishing Corporation 2016 2016-04-20 /pmc/articles/PMC4854988/ /pubmed/27199613 http://dx.doi.org/10.1155/2016/2549616 Text en Copyright © 2016 Lester Wai Mon Chan et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Chan, Lester Wai Mon
Imanishi, Jungo
Ngan, Samuel Y.
Chander, Sarat
Chu, Julie
Thorson, Renae
Pang, Grant
Choong, Peter
Extracorporeal Irradiation and Reimplantation with Total Hip Arthroplasty for Periacetabular Pelvic Resections: A Review of 9 Cases
title Extracorporeal Irradiation and Reimplantation with Total Hip Arthroplasty for Periacetabular Pelvic Resections: A Review of 9 Cases
title_full Extracorporeal Irradiation and Reimplantation with Total Hip Arthroplasty for Periacetabular Pelvic Resections: A Review of 9 Cases
title_fullStr Extracorporeal Irradiation and Reimplantation with Total Hip Arthroplasty for Periacetabular Pelvic Resections: A Review of 9 Cases
title_full_unstemmed Extracorporeal Irradiation and Reimplantation with Total Hip Arthroplasty for Periacetabular Pelvic Resections: A Review of 9 Cases
title_short Extracorporeal Irradiation and Reimplantation with Total Hip Arthroplasty for Periacetabular Pelvic Resections: A Review of 9 Cases
title_sort extracorporeal irradiation and reimplantation with total hip arthroplasty for periacetabular pelvic resections: a review of 9 cases
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854988/
https://www.ncbi.nlm.nih.gov/pubmed/27199613
http://dx.doi.org/10.1155/2016/2549616
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