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Hepatitis C Virus NS5A Protein Triggers Oxidative Stress by Inducing NADPH Oxidases 1 and 4 and Cytochrome P450 2E1

Replication of hepatitis C virus (HCV) is associated with the induction of oxidative stress, which is thought to play a major role in various liver pathologies associated with chronic hepatitis C. NS5A protein of the virus is one of the two key viral proteins that are known to trigger production of...

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Detalles Bibliográficos
Autores principales: Smirnova, Olga A., Ivanova, Olga N., Bartosch, Birke, Valuev-Elliston, Vladimir T., Mukhtarov, Furkat, Kochetkov, Sergey N., Ivanov, Alexander V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855014/
https://www.ncbi.nlm.nih.gov/pubmed/27200149
http://dx.doi.org/10.1155/2016/8341937