NKX6.1 functions as a metastatic suppressor through epigenetic regulation of the epithelial–mesenchymal transition

The transcription factor NKX6.1 (NK6 homeobox 1) is important in the development of pancreatic β-cells and neurons. Although recent publications show that NKX6.1 is hypermethylated and downregulated during tumorigenesis, the function of NKX6.1 in carcinogenesis remains elusive. Here, we address the...

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Detalles Bibliográficos
Autores principales: Li, H-J, Yu, P-N, Huang, K-Y, Su, H-Y, Hsiao, T-H, Chang, C-P, Yu, M-H, Lin, Y-W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855079/
https://www.ncbi.nlm.nih.gov/pubmed/26257059
http://dx.doi.org/10.1038/onc.2015.289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855079/
https://www.ncbi.nlm.nih.gov/pubmed/26257059
http://dx.doi.org/10.1038/onc.2015.289

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