Functional differences in hepatitis C virus nonstructural (NS) 3/4A- and 5A-specific T cell responses

The hepatitis C virus nonstructural (NS) 3/4A and NS5A proteins are major targets for the new direct-acting antiviral compounds. Both viral proteins have been suggested as modulators of the response to the host cell. We have shown that NS3/4A- and NS5A-specific T cell receptors confer different effe...

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Detalles Bibliográficos
Autores principales: Holmström, Fredrik, Chen, Margaret, Balasiddaiah, Anangi, Sällberg, Matti, Ahlén, Gustaf, Frelin, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855235/
https://www.ncbi.nlm.nih.gov/pubmed/27141891
http://dx.doi.org/10.1038/srep24991

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855235/
https://www.ncbi.nlm.nih.gov/pubmed/27141891
http://dx.doi.org/10.1038/srep24991

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