Cargando…
Functional differences in hepatitis C virus nonstructural (NS) 3/4A- and 5A-specific T cell responses
The hepatitis C virus nonstructural (NS) 3/4A and NS5A proteins are major targets for the new direct-acting antiviral compounds. Both viral proteins have been suggested as modulators of the response to the host cell. We have shown that NS3/4A- and NS5A-specific T cell receptors confer different effe...
Autores principales: | Holmström, Fredrik, Chen, Margaret, Balasiddaiah, Anangi, Sällberg, Matti, Ahlén, Gustaf, Frelin, Lars |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855235/ https://www.ncbi.nlm.nih.gov/pubmed/27141891 http://dx.doi.org/10.1038/srep24991 |
Ejemplares similares
-
Immune-mediated effects targeting hepatitis C virus in a syngeneic replicon cell transplantation mouse model
por: Levander, Sepideh, et al.
Publicado: (2018) -
Functional Aspects of Intrahepatic Hepatitis B Virus-specific T Cells Induced by Therapeutic DNA Vaccination
por: Brass, Anette, et al.
Publicado: (2015) -
A targeted controlled force injection of genetic material in vivo
por: Ahlén, Gustaf, et al.
Publicado: (2016) -
Hepatitis C Virus Nonstructural 3/4A Protein Dampens Inflammation and Contributes to Slow Fibrosis Progression during Chronic Fibrosis In Vivo
por: Bansal, Ruchi, et al.
Publicado: (2015) -
A Heterologous Prime/Boost Vaccination Strategy Enhances the Immunogenicity of Therapeutic Vaccines for Hepatitis C Virus
por: Fournillier, Anne, et al.
Publicado: (2013)