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OX40, PD-1 and CTLA-4 are selectively expressed on tumor-infiltrating T cells in head and neck cancer
The tumor microenvironment of squamous cell carcinoma of the head and neck (SCCHN) has been shown to be immune suppressive. Therefore, strategies aimed at overcoming this issue could have a positive therapeutic impact. Hence, we investigated the expression of the known immune-modulatory proteins OX4...
Autores principales: | Montler, Ryan, Bell, R Bryan, Thalhofer, Colin, Leidner, Rom, Feng, Zipei, Fox, Bernard A, Cheng, Allen C, Bui, Tuan G, Tucker, Christopher, Hoen, Helena, Weinberg, Andrew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855266/ https://www.ncbi.nlm.nih.gov/pubmed/27195113 http://dx.doi.org/10.1038/cti.2016.16 |
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