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OX40, PD-1 and CTLA-4 are selectively expressed on tumor-infiltrating T cells in head and neck cancer

The tumor microenvironment of squamous cell carcinoma of the head and neck (SCCHN) has been shown to be immune suppressive. Therefore, strategies aimed at overcoming this issue could have a positive therapeutic impact. Hence, we investigated the expression of the known immune-modulatory proteins OX4...

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Detalles Bibliográficos
Autores principales: Montler, Ryan, Bell, R Bryan, Thalhofer, Colin, Leidner, Rom, Feng, Zipei, Fox, Bernard A, Cheng, Allen C, Bui, Tuan G, Tucker, Christopher, Hoen, Helena, Weinberg, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855266/
https://www.ncbi.nlm.nih.gov/pubmed/27195113
http://dx.doi.org/10.1038/cti.2016.16

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