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Active transforming growth factor-β is associated with phenotypic changes in granulomas after drug treatment in pulmonary tuberculosis

BACKGROUND: Tuberculosis (TB) chemotherapy clears bacterial burden in the lungs of patients and allows the tuberculous lesions to heal through a fibrotic process. The healing process leaves pulmonary scar tissue that can impair lung function. The goal of this study was to identify fibrotic mediators...

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Detalles Bibliográficos
Autores principales:	DiFazio, Robert M., Mattila, Joshua T., Klein, Edwin C., Cirrincione, Lauren R., Howard, Mondraya, Wong, Eileen A., Flynn, JoAnne L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855369/ https://www.ncbi.nlm.nih.gov/pubmed/27148404 http://dx.doi.org/10.1186/s13069-016-0043-3

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