Whole organism transcriptome analysis of zebrafish models of Bardet-Biedl Syndrome and Alström Syndrome provides mechanistic insight into shared and divergent phenotypes

BACKGROUND: Bardet-Biedl Syndrome (BBS) and Alström Syndrome are two pleiotropic ciliopathies with significant phenotypic overlap between them across many tissues. Although BBS and Alström genes are necessary for the proper function of primary cilia, their role in defects across multiple organ syste...

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Detalles Bibliográficos
Autores principales: Hostelley, Timothy L., Lodh, Sukanya, Zaghloul, Norann A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855444/
https://www.ncbi.nlm.nih.gov/pubmed/27142762
http://dx.doi.org/10.1186/s12864-016-2679-1

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