Dorsal root ganglia in Friedreich ataxia: satellite cell proliferation and inflammation

INTRODUCTION: Dorsal root ganglia (DRG) are highly vulnerable to frataxin deficiency in Friedreich ataxia (FA), an autosomal recessive disease due to pathogenic homozygous guanine-adenine-adenine trinucleotide repeat expansions in intron 1 of the FXN gene (chromosome 9q21.11). An immunohistochemical...

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Detalles Bibliográficos
Autores principales: Koeppen, Arnulf H., Ramirez, R. Liane, Becker, Alyssa B., Mazurkiewicz, Joseph E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855486/
https://www.ncbi.nlm.nih.gov/pubmed/27142428
http://dx.doi.org/10.1186/s40478-016-0288-5

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