Cargando…
Modified platelet deposition on matrix metalloproteinase 13 digested collagen I
BACKGROUND: Atherothrombosis underlies acute coronary syndromes, including unstable angina and acute myocardial infarction. Within the unstable plaque, monocytes express collagenolytic matrix metalloproteinases (MMPs), including MMP‐13, which degrades fibrous collagen. Following rupture, vessel wall...
Autores principales: | Howes, J.‐M., Pugh, N., Knäuper, V., Farndale, R. W. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855633/ https://www.ncbi.nlm.nih.gov/pubmed/26447617 http://dx.doi.org/10.1111/jth.13166 |
Ejemplares similares
-
Cleavage by MMP‐13 renders VWF unable to bind to collagen but increases its platelet reactivity
por: Howes, Joanna‐Marie, et al.
Publicado: (2020) -
Platelet collagen receptor Glycoprotein VI‐dimer recognizes fibrinogen and fibrin through their D‐domains, contributing to platelet adhesion and activation during thrombus formation
por: Induruwa, I., et al.
Publicado: (2018) -
Multimerin 1 supports platelet function in vivo and binds to specific GPAGPOGPX motifs in fibrillar collagens that enhance platelet adhesion
por: Leatherdale, Alexander, et al.
Publicado: (2020) -
The chaperone protein HSP47: a platelet collagen binding protein that contributes to thrombosis and hemostasis
por: Sasikumar, P., et al.
Publicado: (2018) -
Clustering of glycoprotein VI (GPVI) dimers upon adhesion to collagen as a mechanism to regulate GPVI signaling in platelets
por: Poulter, N. S., et al.
Publicado: (2017)