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Alcohol Consumption in Relation to Risk and Severity of Chronic Widespread Pain: Results From a UK Population‐Based Study

OBJECTIVE: To determine whether the reported level of alcohol consumption is associated with the likelihood of reporting chronic widespread pain (CWP) and, among persons with CWP, the associated disability. METHODS: In a population‐based study in 2 areas of the UK, participants self‐completed a post...

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Autores principales: Macfarlane, Gary J., Beasley, Marcus, Prescott, Gordon J., McNamee, Paul, Hannaford, Philip C., McBeth, John, Lovell, Karina, Keeley, Phil, Symmons, Deborah P. M., Woby, Steve, Norrie, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855637/
https://www.ncbi.nlm.nih.gov/pubmed/26212017
http://dx.doi.org/10.1002/acr.22604
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author Macfarlane, Gary J.
Beasley, Marcus
Prescott, Gordon J.
McNamee, Paul
Hannaford, Philip C.
McBeth, John
Lovell, Karina
Keeley, Phil
Symmons, Deborah P. M.
Woby, Steve
Norrie, John
author_facet Macfarlane, Gary J.
Beasley, Marcus
Prescott, Gordon J.
McNamee, Paul
Hannaford, Philip C.
McBeth, John
Lovell, Karina
Keeley, Phil
Symmons, Deborah P. M.
Woby, Steve
Norrie, John
author_sort Macfarlane, Gary J.
collection PubMed
description OBJECTIVE: To determine whether the reported level of alcohol consumption is associated with the likelihood of reporting chronic widespread pain (CWP) and, among persons with CWP, the associated disability. METHODS: In a population‐based study in 2 areas of the UK, participants self‐completed a postal questionnaire. They were classified according to whether they met the American College of Rheumatology definition of CWP and whether the pain was disabling (Chronic Pain Grade III or IV). They reported their usual level of alcohol consumption. Potential confounding factors on which information was available included age, sex, cigarette smoking, employment status, self‐reported weight and height, and level of deprivation. RESULTS: A total of 13,574 persons participated (mean age 55 years, 57% women) of whom 2,239 (16.5%) had CWP; 28% reported never regularly consuming alcohol, 28% reported consuming up to 5 units/week, 20% reported 6–10 units/week, and 24% reported >10 units/week. Among persons with CWP, disability was strongly linked to level of alcohol consumption. Prevalence of disability decreased with increasing alcohol consumption up to 35 units/week (odds ratio [OR](21–35 units alcohol/week versus never drinkers) 0.33 [95% confidence interval (95% CI) 0.19–0.58]) adjusted for confounders. A similar relationship was found between reporting CWP and level of alcohol consumption (adjusted OR(21–35 units alcohol/week versus never drinkers) 0.76 [95% CI 0.61–0.94]). CONCLUSION: This study has demonstrated strong associations between level of alcohol consumption and both CWP and related disabilities. However, the available evidence does not allow us to conclude that the association is causal. The strength of the associations means that specific studies to examine this potential relationship are warranted.
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spelling pubmed-48556372016-06-22 Alcohol Consumption in Relation to Risk and Severity of Chronic Widespread Pain: Results From a UK Population‐Based Study Macfarlane, Gary J. Beasley, Marcus Prescott, Gordon J. McNamee, Paul Hannaford, Philip C. McBeth, John Lovell, Karina Keeley, Phil Symmons, Deborah P. M. Woby, Steve Norrie, John Arthritis Care Res (Hoboken) Pain OBJECTIVE: To determine whether the reported level of alcohol consumption is associated with the likelihood of reporting chronic widespread pain (CWP) and, among persons with CWP, the associated disability. METHODS: In a population‐based study in 2 areas of the UK, participants self‐completed a postal questionnaire. They were classified according to whether they met the American College of Rheumatology definition of CWP and whether the pain was disabling (Chronic Pain Grade III or IV). They reported their usual level of alcohol consumption. Potential confounding factors on which information was available included age, sex, cigarette smoking, employment status, self‐reported weight and height, and level of deprivation. RESULTS: A total of 13,574 persons participated (mean age 55 years, 57% women) of whom 2,239 (16.5%) had CWP; 28% reported never regularly consuming alcohol, 28% reported consuming up to 5 units/week, 20% reported 6–10 units/week, and 24% reported >10 units/week. Among persons with CWP, disability was strongly linked to level of alcohol consumption. Prevalence of disability decreased with increasing alcohol consumption up to 35 units/week (odds ratio [OR](21–35 units alcohol/week versus never drinkers) 0.33 [95% confidence interval (95% CI) 0.19–0.58]) adjusted for confounders. A similar relationship was found between reporting CWP and level of alcohol consumption (adjusted OR(21–35 units alcohol/week versus never drinkers) 0.76 [95% CI 0.61–0.94]). CONCLUSION: This study has demonstrated strong associations between level of alcohol consumption and both CWP and related disabilities. However, the available evidence does not allow us to conclude that the association is causal. The strength of the associations means that specific studies to examine this potential relationship are warranted. John Wiley and Sons Inc. 2015-08-26 2015-09 /pmc/articles/PMC4855637/ /pubmed/26212017 http://dx.doi.org/10.1002/acr.22604 Text en © 2015 The Authors. Arthritis Care & Research is published by Wiley Periodicals, Inc. on behalf of the American College of Rheumatology. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Pain
Macfarlane, Gary J.
Beasley, Marcus
Prescott, Gordon J.
McNamee, Paul
Hannaford, Philip C.
McBeth, John
Lovell, Karina
Keeley, Phil
Symmons, Deborah P. M.
Woby, Steve
Norrie, John
Alcohol Consumption in Relation to Risk and Severity of Chronic Widespread Pain: Results From a UK Population‐Based Study
title Alcohol Consumption in Relation to Risk and Severity of Chronic Widespread Pain: Results From a UK Population‐Based Study
title_full Alcohol Consumption in Relation to Risk and Severity of Chronic Widespread Pain: Results From a UK Population‐Based Study
title_fullStr Alcohol Consumption in Relation to Risk and Severity of Chronic Widespread Pain: Results From a UK Population‐Based Study
title_full_unstemmed Alcohol Consumption in Relation to Risk and Severity of Chronic Widespread Pain: Results From a UK Population‐Based Study
title_short Alcohol Consumption in Relation to Risk and Severity of Chronic Widespread Pain: Results From a UK Population‐Based Study
title_sort alcohol consumption in relation to risk and severity of chronic widespread pain: results from a uk population‐based study
topic Pain
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855637/
https://www.ncbi.nlm.nih.gov/pubmed/26212017
http://dx.doi.org/10.1002/acr.22604
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