Cargando…

Targeting the epigenetics of the DNA damage response in breast cancer

Cancer is as much an epigenetic disease as it is a genetic disease, and epigenetic alterations in cancer often serve as potent surrogates for genetic mutations. Because the epigenetic factors involved in the DNA damage response are regulated by multiple elements, therapies to target specific compone...

Descripción completa

Detalles Bibliográficos
Autores principales:	Montenegro, M F, González-Guerrero, R, Sánchez-del-Campo, L, Piñero-Madrona, A, Cabezas-Herrera, J, Rodríguez-López, J N
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855664/ https://www.ncbi.nlm.nih.gov/pubmed/27054335 http://dx.doi.org/10.1038/cddis.2016.85

Ejemplares similares

PRMT1-dependent methylation of BRCA1 contributes to the epigenetic defense of breast cancer cells against ionizing radiation
por: Montenegro, María F., et al.
Publicado: (2020)

Reactivation of the Tumour Suppressor RASSF1A in Breast Cancer by Simultaneous Targeting of DNA and E2F1 Methylation
por: Montenegro, María F., et al.
Publicado: (2012)

MITF induces escape from innate immunity in melanoma
por: Sánchez-del-Campo, Luis, et al.
Publicado: (2021)

Targeting protein methylation in pancreatic cancer cells results in KRAS signaling imbalance and inhibition of autophagy
por: Montenegro, María F., et al.
Publicado: (2023)

Acriflavine, a Potent Inhibitor of HIF-1α, Disturbs Glucose Metabolism and Suppresses ATF4-Protective Pathways in Melanoma under Non-hypoxic Conditions
por: Martí-Díaz, Román, et al.
Publicado: (2020)

Epigenetics, DNA damage, and aging
por: Soto-Palma, Carolina, et al.
Publicado: (2022)

Targeting Histone Epigenetic Modifications and DNA Damage Responses in Synthetic Lethality Strategies in Cancer?
por: Lazo, Pedro A.
Publicado: (2022)

Thallium-induced DNA damage, genetic, and epigenetic alterations
por: Sánchez-Chapul, Laura, et al.
Publicado: (2023)

Targeting DNA Damage Response in Prostate and Breast Cancer
por: Wengner, Antje M., et al.
Publicado: (2020)

Epigenetic Telomere Protection by Drosophila DNA Damage Response Pathways
por: Oikemus, Sarah R, et al.
Publicado: (2006)

Role of some epigenetic factors in DNA damage response pathway
por: Tiwari, Mrinalini, et al.
Publicado: (2017)

Binding of Natural and Synthetic Polyphenols to Human Dihydrofolate Reductase
por: Sánchez-del-Campo, Luís, et al.
Publicado: (2009)

DNA Damage: Epigenetics, Aging and Rejuvenation
por: Sinclair, David
Publicado: (2020)

The Role of SIRT1 on DNA Damage Response and Epigenetic Alterations in Cancer
por: Alves-Fernandes, Débora Kristina, et al.
Publicado: (2019)

Resolving DNA Damage: Epigenetic Regulation of DNA Repair
por: Karakaidos, Panagiotis, et al.
Publicado: (2020)

Targeting the DNA damage response for cancer therapy
por: Curtin, Nicola J.
Publicado: (2023)

COVID-19 Confinement Effects on Game Actions during Competition Restart in Professional Soccer Players
por: García-Aliaga, Abraham, et al.
Publicado: (2022)

Isolated tumour cells and micrometastases in intraductal breast cancer: a simple mechanical question in some cases
por: Piñero-Madrona, A, et al.
Publicado: (2013)

Nucleic Acid Oxidation in DNA Damage Repair and Epigenetics
por: Zheng, Guanqun, et al.
Publicado: (2014)

Epigenetic mechanisms behind cellular sensitivity to DNA damage
por: Williamson, Amanda K., et al.
Publicado: (2018)

Targeting DNA damage response in cancer therapy
por: Hosoya, Noriko, et al.
Publicado: (2014)

Therapeutic Targeting of DNA Damage Response in Cancer
por: Choi, Wonyoung, et al.
Publicado: (2022)

Targeting the DNA Damage Response for Cancer Therapy
por: Wang, Ruoxi, et al.
Publicado: (2023)

Lower limb cutaneous melanoma surgery: location matters
por: Piñero-Madrona, Antonio, et al.
Publicado: (2023)

DUBbing Cancer: Deubiquitylating Enzymes Involved in Epigenetics, DNA Damage and the Cell Cycle As Therapeutic Targets
por: Pinto-Fernandez, Adan, et al.
Publicado: (2016)

Global distributed applications with Windows DNA /
por: Madrona, Enrique
Publicado: (2000)

DNA methylation data for identification of epigenetic targets of resveratrol in triple negative breast cancer cells
por: Medina-Aguilar, Rubiceli, et al.
Publicado: (2017)

Transcriptomal profiling of the cellular response to DNA damage mediated by Slug (Snai2)
por: Pérez-Caro, M, et al.
Publicado: (2008)

Targeting the DNA Damage Response for the Treatment of High Risk Neuroblastoma
por: Southgate, Harriet E. D., et al.
Publicado: (2020)

Epigenetic regulation of TP53 is involved in prostate cancer radioresistance and DNA damage response signaling
por: Macedo-Silva, Catarina, et al.
Publicado: (2023)

Chromatin Remodeling and Epigenetic Regulation in Plant DNA Damage Repair
por: Kim, Jin-Hong
Publicado: (2019)

Epigenetic control of gene function in schistosomes: a source of therapeutic targets?
por: Cabezas-Cruz, Alejandro, et al.
Publicado: (2014)

Strategies for targeting the DNA damage response for cancer therapeutics
por: Zhang, Dan, et al.
Publicado: (2012)

Targeting DNA Damage Response and Replication Stress in Pancreatic Cancer
por: Dreyer, Stephan B., et al.
Publicado: (2021)

Fun30 and Rtt109 Mediate Epigenetic Regulation of the DNA Damage Response Pathway in C. albicans
por: Maurya, Prashant Kumar, et al.
Publicado: (2022)

Controlling the response to DNA damage by the APC/C-Cdh1
por: de Boer, H. Rudolf, et al.
Publicado: (2015)

Targeting DNA Damage Response as a Strategy to Treat HPV Infections
por: Banerjee, N. Sanjib, et al.
Publicado: (2019)

Impact of DNA Damage Response—Targeted Therapies on the Immune Response to Tumours
por: Lutfi, Nura, et al.
Publicado: (2021)

Environmental Exposures during Puberty: Window of Breast Cancer Risk and Epigenetic Damage
por: Natarajan, Rama, et al.
Publicado: (2020)

Modulation of SLFN11 induces changes in DNA Damage response in breast cancer
por: Raynaud, Christophe Michel, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_kq0vdb7fhrltn5f4u9ahkbkeoo