Parthenolide and DMAPT exert cytotoxic effects on breast cancer stem-like cells by inducing oxidative stress, mitochondrial dysfunction and necrosis

Triple-negative breast cancers (TNBCs) are aggressive forms of breast carcinoma associated with a high rate of recidivism. In this paper, we report the production of mammospheres from three lines of TNBC cells and demonstrate that both parthenolide (PN) and its soluble analog dimethylaminoparthenoli...

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Detalles Bibliográficos
Autores principales: Carlisi, D, Buttitta, G, Di Fiore, R, Scerri, C, Drago-Ferrante, R, Vento, R, Tesoriere, G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855673/
https://www.ncbi.nlm.nih.gov/pubmed/27077810
http://dx.doi.org/10.1038/cddis.2016.94

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855673/
https://www.ncbi.nlm.nih.gov/pubmed/27077810
http://dx.doi.org/10.1038/cddis.2016.94

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