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A dual role for AMP‐activated protein kinase (AMPK) during neonatal hypoxic–ischaemic brain injury in mice

Perinatal hypoxic–ischaemic encephalopathy (HIE) occurs in 1–2 in every 1000 term infants and the devastating consequences range from cerebral palsy, epilepsy and neurological deficit to death. Cellular damage post insult occurs after a delay and is mediated by a secondary neural energy failure. AMP...

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Detalles Bibliográficos
Autores principales: Rousset, Catherine I., Leiper, Fiona C., Kichev, Anton, Gressens, Pierre, Carling, David, Hagberg, Henrik, Thornton, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855681/
https://www.ncbi.nlm.nih.gov/pubmed/25598140
http://dx.doi.org/10.1111/jnc.13034