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Evidence for a role of adaptive immune response in the disease pathogenesis of the MPTP mouse model of Parkinson's disease

Parkinson's disease (PD) is the second most common neurodegenerative disease and results from the loss of dopaminergic neurons of the nigrostriatal pathway. The pathogenesis of PD is poorly understood, but inflammatory processes have been implicated. Indeed increases in the number of major hist...

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Detalles Bibliográficos
Autores principales: Martin, Heather L., Santoro, Matteo, Mustafa, Sarah, Riedel, Gernot, Forrester, John V., Teismann, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855685/
https://www.ncbi.nlm.nih.gov/pubmed/26511587
http://dx.doi.org/10.1002/glia.22935