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Epithelial cell lines of the cotton rat (Sigmodon hispidus) are highly susceptible in vitro models to zoonotic Bunya-, Rhabdo-, and Flaviviruses

BACKGROUND: Small mammals such as bats and rodents have been increasingly recognized as reservoirs of novel potentially zoonotic pathogens. However, few in vitro model systems to date allow assessment of zoonotic viruses in a relevant host context. The cotton rat (Sigmodon hispidus) is a New World r...

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Detalles Bibliográficos
Autores principales: Ehlen, Lukas, Tödtmann, Jan, Specht, Sabine, Kallies, René, Papies, Jan, Müller, Marcel A., Junglen, Sandra, Drosten, Christian, Eckerle, Isabella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855710/
https://www.ncbi.nlm.nih.gov/pubmed/27142375
http://dx.doi.org/10.1186/s12985-016-0531-5