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Poly-arginine peptides reduce infarct volume in a permanent middle cerebral artery rat stroke model
BACKGROUND: We recently reported that poly-arginine peptides have neuroprotective properties both in vitro and in vivo. In cultured cortical neurons exposed to glutamic acid excitotoxicity, we demonstrated that neuroprotective potency increases with polymer length plateauing at R15 to R18 (R = argin...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855717/ https://www.ncbi.nlm.nih.gov/pubmed/27142074 http://dx.doi.org/10.1186/s12868-016-0253-z |