Poly-arginine peptides reduce infarct volume in a permanent middle cerebral artery rat stroke model

BACKGROUND: We recently reported that poly-arginine peptides have neuroprotective properties both in vitro and in vivo. In cultured cortical neurons exposed to glutamic acid excitotoxicity, we demonstrated that neuroprotective potency increases with polymer length plateauing at R15 to R18 (R = argin...

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Detalles Bibliográficos
Autores principales: Milani, Diego, Clark, Vince W., Cross, Jane L., Anderton, Ryan S., Knuckey, Neville W., Meloni, Bruno P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855717/
https://www.ncbi.nlm.nih.gov/pubmed/27142074
http://dx.doi.org/10.1186/s12868-016-0253-z

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