Type B insulin resistance syndrome with Scleroderma successfully treated with multiple immune suppressants after eradication of Helicobacter pylori infection: a case report

BACKGROUND: Type B insulin resistance is a rare autoimmune disease characterized by the presence of autoantibodies against the insulin receptor. Helicobacter pylori (H pylori) infection may play a causative role in the autoimmune diseases. CASE PRESENTATION: Here, we present a rare case of a 48-year...

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Autores principales: Yang, Guo-Qing, Li, Yi-Jun, Dou, Jing-Tao, Wang, Bao-An, Lu, Ju-Ming, Mu, Yi-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855773/
https://www.ncbi.nlm.nih.gov/pubmed/27142369
http://dx.doi.org/10.1186/s12902-016-0099-5
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author Yang, Guo-Qing
Li, Yi-Jun
Dou, Jing-Tao
Wang, Bao-An
Lu, Ju-Ming
Mu, Yi-Ming
author_facet Yang, Guo-Qing
Li, Yi-Jun
Dou, Jing-Tao
Wang, Bao-An
Lu, Ju-Ming
Mu, Yi-Ming
author_sort Yang, Guo-Qing
collection PubMed
description BACKGROUND: Type B insulin resistance is a rare autoimmune disease characterized by the presence of autoantibodies against the insulin receptor. Helicobacter pylori (H pylori) infection may play a causative role in the autoimmune diseases. CASE PRESENTATION: Here, we present a rare case of a 48-year old female patient, who had type B insulin resistance with systemic scleroderma and was successfully treated with multiple immune suppressants after eradication of Helicobacter pylori infection. CONCLUSION: The present case suggests H pylori infection-related pathological mechanism may contribute to type B insulin resistance syndrome and autoimmune disorders. Treatment toward H pylori may be helpful to relieve syndrome of type B insulin resistance for H pylori positive patients.
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spelling pubmed-48557732016-05-05 Type B insulin resistance syndrome with Scleroderma successfully treated with multiple immune suppressants after eradication of Helicobacter pylori infection: a case report Yang, Guo-Qing Li, Yi-Jun Dou, Jing-Tao Wang, Bao-An Lu, Ju-Ming Mu, Yi-Ming BMC Endocr Disord Case Report BACKGROUND: Type B insulin resistance is a rare autoimmune disease characterized by the presence of autoantibodies against the insulin receptor. Helicobacter pylori (H pylori) infection may play a causative role in the autoimmune diseases. CASE PRESENTATION: Here, we present a rare case of a 48-year old female patient, who had type B insulin resistance with systemic scleroderma and was successfully treated with multiple immune suppressants after eradication of Helicobacter pylori infection. CONCLUSION: The present case suggests H pylori infection-related pathological mechanism may contribute to type B insulin resistance syndrome and autoimmune disorders. Treatment toward H pylori may be helpful to relieve syndrome of type B insulin resistance for H pylori positive patients. BioMed Central 2016-05-03 /pmc/articles/PMC4855773/ /pubmed/27142369 http://dx.doi.org/10.1186/s12902-016-0099-5 Text en © Yang et al. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Yang, Guo-Qing
Li, Yi-Jun
Dou, Jing-Tao
Wang, Bao-An
Lu, Ju-Ming
Mu, Yi-Ming
Type B insulin resistance syndrome with Scleroderma successfully treated with multiple immune suppressants after eradication of Helicobacter pylori infection: a case report
title Type B insulin resistance syndrome with Scleroderma successfully treated with multiple immune suppressants after eradication of Helicobacter pylori infection: a case report
title_full Type B insulin resistance syndrome with Scleroderma successfully treated with multiple immune suppressants after eradication of Helicobacter pylori infection: a case report
title_fullStr Type B insulin resistance syndrome with Scleroderma successfully treated with multiple immune suppressants after eradication of Helicobacter pylori infection: a case report
title_full_unstemmed Type B insulin resistance syndrome with Scleroderma successfully treated with multiple immune suppressants after eradication of Helicobacter pylori infection: a case report
title_short Type B insulin resistance syndrome with Scleroderma successfully treated with multiple immune suppressants after eradication of Helicobacter pylori infection: a case report
title_sort type b insulin resistance syndrome with scleroderma successfully treated with multiple immune suppressants after eradication of helicobacter pylori infection: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855773/
https://www.ncbi.nlm.nih.gov/pubmed/27142369
http://dx.doi.org/10.1186/s12902-016-0099-5
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