Expression of the cereblon binding protein argonaute 2 plays an important role for multiple myeloma cell growth and survival

BACKGROUND: Immunomodulatory drugs (IMiDs), such as lenalidomide, are therapeutically active compounds that bind and modulate the E3 ubiquitin ligase substrate recruiter cereblon, thereby affect steady-state levels of cereblon and cereblon binding partners, such as ikaros and aiolos, and induce many...

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Detalles Bibliográficos
Autores principales: Xu, Qinqin, Hou, Yue-xian, Langlais, Paul, Erickson, Patrick, Zhu, James, Shi, Chang-Xin, Luo, Moulun, Zhu, Yuanxiao, Xu, Ye, Mandarino, Lawrence J., Stewart, Keith, Chang, Xiu-bao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855823/
https://www.ncbi.nlm.nih.gov/pubmed/27142104
http://dx.doi.org/10.1186/s12885-016-2331-0

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