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Treatment Paradigms for Retinal and Macular Diseases Using 3-D Retina Cultures Derived From Human Reporter Pluripotent Stem Cell Lines
We discuss the use of pluripotent stem cell lines carrying fluorescent reporters driven by retinal promoters to derive three-dimensional (3-D) retina in culture and how this system can be exploited for elucidating human retinal biology, creating disease models in a dish, and designing targeted drug...
Autores principales: | Kaewkhaw, Rossukon, Swaroop, Manju, Homma, Kohei, Nakamura, Jutaro, Brooks, Matthew, Kaya, Koray Dogan, Chaitankar, Vijender, Michael, Sam, Tawa, Gregory, Zou, Jizhong, Rao, Mahendra, Zheng, Wei, Cogliati, Tiziana, Swaroop, Anand |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855830/ https://www.ncbi.nlm.nih.gov/pubmed/27116668 http://dx.doi.org/10.1167/iovs.15-17639 |
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