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A principal components method constrained by elementary flux modes: analysis of flux data sets
BACKGROUND: Non-negative linear combinations of elementary flux modes (EMs) describe all feasible reaction flux distributions for a given metabolic network under the quasi steady state assumption. However, only a small subset of EMs contribute to the physiological state of a given cell. RESULTS: In...
Autores principales: | von Stosch, Moritz, Rodrigues de Azevedo, Cristiana, Luis, Mauro, Feyo de Azevedo, Sebastiao, Oliveira, Rui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855838/ https://www.ncbi.nlm.nih.gov/pubmed/27146133 http://dx.doi.org/10.1186/s12859-016-1063-0 |
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