Prostate Cancer With Metastatic Lytic Bone Lesions: Positive Bone Scan Post Docetaxel Chemotherapy in the Setting of Clinically Successful Treatment

Current treatment of metastatic bone prostate cancer with Docetaxel chemotherapy per CHAARTED trial is standard of care. Timing of CT and bone scintigraphy for evaluation of successful treatment of lytic lesions is not available in the literature. We present a case of a 70 year old male with PSA of...

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Autores principales: Bird, Victoria Yvonne, Domino, Paula M., Sutkowski, Raymond, Stillings, Stephanie A., Trejo-Lopez, Jorge A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855904/
https://www.ncbi.nlm.nih.gov/pubmed/27169018
http://dx.doi.org/10.1016/j.eucr.2015.12.008
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author Bird, Victoria Yvonne
Domino, Paula M.
Sutkowski, Raymond
Stillings, Stephanie A.
Trejo-Lopez, Jorge A.
author_facet Bird, Victoria Yvonne
Domino, Paula M.
Sutkowski, Raymond
Stillings, Stephanie A.
Trejo-Lopez, Jorge A.
author_sort Bird, Victoria Yvonne
collection PubMed
description Current treatment of metastatic bone prostate cancer with Docetaxel chemotherapy per CHAARTED trial is standard of care. Timing of CT and bone scintigraphy for evaluation of successful treatment of lytic lesions is not available in the literature. We present a case of a 70 year old male with PSA of 586 and wide spread metastatic bone lytic lesions, who underwent androgen deprivation therapy and six cycles of Docetaxel chemotherapy. The patient had clinically successful treatment. Contrast enhanced CT scan demonstrated sclerotic bone lesions with PSA 2.5 at this point in treatment; however, 99mTc-MDP bone scintigraphy remained positive for metastatic lesions.
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spelling pubmed-48559042016-05-10 Prostate Cancer With Metastatic Lytic Bone Lesions: Positive Bone Scan Post Docetaxel Chemotherapy in the Setting of Clinically Successful Treatment Bird, Victoria Yvonne Domino, Paula M. Sutkowski, Raymond Stillings, Stephanie A. Trejo-Lopez, Jorge A. Urol Case Rep Oncology Current treatment of metastatic bone prostate cancer with Docetaxel chemotherapy per CHAARTED trial is standard of care. Timing of CT and bone scintigraphy for evaluation of successful treatment of lytic lesions is not available in the literature. We present a case of a 70 year old male with PSA of 586 and wide spread metastatic bone lytic lesions, who underwent androgen deprivation therapy and six cycles of Docetaxel chemotherapy. The patient had clinically successful treatment. Contrast enhanced CT scan demonstrated sclerotic bone lesions with PSA 2.5 at this point in treatment; however, 99mTc-MDP bone scintigraphy remained positive for metastatic lesions. Elsevier 2016-02-22 /pmc/articles/PMC4855904/ /pubmed/27169018 http://dx.doi.org/10.1016/j.eucr.2015.12.008 Text en © 2016 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Oncology
Bird, Victoria Yvonne
Domino, Paula M.
Sutkowski, Raymond
Stillings, Stephanie A.
Trejo-Lopez, Jorge A.
Prostate Cancer With Metastatic Lytic Bone Lesions: Positive Bone Scan Post Docetaxel Chemotherapy in the Setting of Clinically Successful Treatment
title Prostate Cancer With Metastatic Lytic Bone Lesions: Positive Bone Scan Post Docetaxel Chemotherapy in the Setting of Clinically Successful Treatment
title_full Prostate Cancer With Metastatic Lytic Bone Lesions: Positive Bone Scan Post Docetaxel Chemotherapy in the Setting of Clinically Successful Treatment
title_fullStr Prostate Cancer With Metastatic Lytic Bone Lesions: Positive Bone Scan Post Docetaxel Chemotherapy in the Setting of Clinically Successful Treatment
title_full_unstemmed Prostate Cancer With Metastatic Lytic Bone Lesions: Positive Bone Scan Post Docetaxel Chemotherapy in the Setting of Clinically Successful Treatment
title_short Prostate Cancer With Metastatic Lytic Bone Lesions: Positive Bone Scan Post Docetaxel Chemotherapy in the Setting of Clinically Successful Treatment
title_sort prostate cancer with metastatic lytic bone lesions: positive bone scan post docetaxel chemotherapy in the setting of clinically successful treatment
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855904/
https://www.ncbi.nlm.nih.gov/pubmed/27169018
http://dx.doi.org/10.1016/j.eucr.2015.12.008
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