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Staufen Negatively Modulates MicroRNA Activity in Caenorhabditis elegans

The double-stranded RNA-binding protein Staufen has been implicated in various posttranscriptional gene regulatory processes. Here, we demonstrate that the Caenorhabditis elegans homolog of Staufen, STAU-1, functionally interacts with microRNAs. Loss-of-function mutations of stau-1 significantly sup...

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Detalles Bibliográficos
Autores principales:	Ren, Zhiji, Veksler-Lublinsky, Isana, Morrissey, David, Ambros, Victor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2016
Materias:	Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856075/ https://www.ncbi.nlm.nih.gov/pubmed/26921297 http://dx.doi.org/10.1534/g3.116.027300

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