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Intrahepatic and extrahepatic aminotransferase elevation associated with clinical‐therapeutic events in a schizophrenic patient

A schizophrenic patient showed rhabdomyolysis with idiopathic transaminitis. The intermixed pattern of intrahepatic and extrahepatic alanine aminotransferase (ALT) elevation is associated with respective clinical‐therapeutic events. Aminotransferases play a role as surrogate biomarkers of “liver met...

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Detalles Bibliográficos
Autores principales: Suzuki, Yoshifumi, Kawashima, Yoshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856238/
https://www.ncbi.nlm.nih.gov/pubmed/27190609
http://dx.doi.org/10.1002/ccr3.546
Descripción
Sumario:A schizophrenic patient showed rhabdomyolysis with idiopathic transaminitis. The intermixed pattern of intrahepatic and extrahepatic alanine aminotransferase (ALT) elevation is associated with respective clinical‐therapeutic events. Aminotransferases play a role as surrogate biomarkers of “liver metabolic functioning” beyond the obsolete classical concept associating ALT elevation only with liver cellular damage.