Cargando…

A Novel Computational Tool for Mining Real-Life Data: Application in the Metastatic Colorectal Cancer Care Setting

BACKGROUND: Randomized clinical trials constitute the gold-standard for evaluating new anti-cancer therapies; however, real-life data are key in complementing clinically useful information. We developed a computational tool for real-life data analysis and applied it to the metastatic colorectal canc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Siegelmann-Danieli, Nava, Farkash, Ariel, Katzir, Itzhak, Vesterman Landes, Janet, Rotem Rabinovich, Hadas, Lomnicky, Yossef, Carmeli, Boaz, Parush-Shear-Yashuv, Naama
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856262/ https://www.ncbi.nlm.nih.gov/pubmed/27144545 http://dx.doi.org/10.1371/journal.pone.0154689

Ejemplares similares

Trends in annual drug expenditure – a 16 year perspective of a public healthcare maintenance organization
por: Lomnicky, Yossef, et al.
Publicado: (2016)

The impact of the Oncotype DX Recurrence Score on treatment decisions and clinical outcomes in patients with early breast cancer: the Maccabi Healthcare Services experience with a unified testing policy
por: Siegelmann-Danieli, Nava, et al.
Publicado: (2013)

Dynamic Computational Model Suggests That Cellular Citizenship Is Fundamental for Selective Tumor Apoptosis
por: Olsen, Megan, et al.
Publicado: (2010)

The reimbursement process in three national healthcare systems: variation in time to reimbursement of pembrolizumab for metastatic non-small cell lung cancer
por: Sharman Moser, Sarah, et al.
Publicado: (2023)

Hormone-Replacement Therapy and Its Association with Breast Cancer Subtypes: A Large Retrospective Cohort Study
por: Rosenberg, Vered, et al.
Publicado: (2021)

Constitutional genetic variation at the human aromatase gene (Cyp19) and breast cancer risk
por: Siegelmann-Danieli, N, et al.
Publicado: (1999)

Dopaminergic Balance between Reward Maximization and Policy Complexity
por: Parush, Naama, et al.
Publicado: (2011)

Real World Analysis of Small Cell Lung Cancer Patients: Prognostic Factors and Treatment Outcomes
por: Moser, Sarah Sharman, et al.
Publicado: (2021)

Elderly Persons with Intellectual Disability: A Study of Clinical Characteristics, Functional Status, and Sensory Capacity
por: Carmeli, Eli, et al.
Publicado: (2003)

Attention-Deficit/Hyperactivity Disorder Symptoms, Sensation-Seeking, and Sensory Modulation Dysfunction in Substance Use Disorder: A Cross Sectional Two-Group Comparative Study
por: Assayag, Naama, et al.
Publicado: (2022)

Estimating tumor mutational burden from RNA-sequencing without a matched-normal sample
por: Katzir, Rotem, et al.
Publicado: (2022)

Visually Guided Avoidance in the Chameleon (Chamaeleo chameleon): Response Patterns and Lateralization
por: Lustig, Avichai, et al.
Publicado: (2012)

Relating Lateralization of Eye Use to Body Motion in the Avoidance Behavior of the Chameleon (Chamaeleo chameleon)
por: Lustig, Avichai, et al.
Publicado: (2013)

A Patient-Centered Information System (myED) for Emergency Care Journeys: Design, Development, and Initial Adoption
por: Westphal, Monika, et al.
Publicado: (2020)

Artifact3-D: New software for accurate, objective and efficient 3D analysis and documentation of archaeological artifacts
por: Grosman, Leore, et al.
Publicado: (2022)

Do Attachment Orientations Relate to Coping with Crises? Lessons from a Cross-Sectional Study during the COVID-19 Pandemic
por: Egozi Farkash, Hadas, et al.
Publicado: (2023)

Human factors in healthcare: a field guide to continuous improvement
por: Parush, Avi, et al.
Publicado: (2017)

Mining the Modular Structure of Protein Interaction Networks
por: Berenstein, Ariel José, et al.
Publicado: (2015)

A system for identifying and investigating unexpected response to treatment
por: Ozery-Flato, Michal, et al.
Publicado: (2015)

Conceptual design for interactive systems: designing for performance and user experience
por: Parush, Avi
Publicado: (2015)

FORMATION OF BONE TISSUE IN CULTURE FROM ISOLATED BONE CELLS
por: Binderman, Itzhak, et al.
Publicado: (1974)

Biology of the Extracellular Proteasome
por: Ben-Nissan, Gili, et al.
Publicado: (2022)

Dynamic Proteomics of Human Protein Level and Localization across the Cell Cycle
por: Farkash-Amar, Shlomit, et al.
Publicado: (2012)

Complex Systems Science and Brain Dynamics
por: Siegelmann, Hava T.
Publicado: (2010)

Interplay between population firing stability and single neuron dynamics in hippocampal networks
por: Slomowitz, Edden, et al.
Publicado: (2015)

Noise Genetics: Inferring Protein Function by Correlating Phenotype with Protein Levels and Localization in Individual Human Cells
por: Farkash-Amar, Shlomit, et al.
Publicado: (2014)

Conservation of Resources, Psychological Distress, and Resilience During the COVID-19 Pandemic
por: Egozi Farkash, Hadas, et al.
Publicado: (2022)

Evaluation of Automated Ribosomal Intergenic Spacer Analysis for Bacterial Fingerprinting of Rumen Microbiome Compared to Pyrosequencing Technology
por: Jami, Elie, et al.
Publicado: (2014)

Computer-Based Identification of a Novel LIMK1/2 Inhibitor that Synergizes with Salirasib to Destabilize the Actin Cytoskeleton
por: Mashiach-Farkash, Efrat, et al.
Publicado: (2012)

The impact of antibiotic use on transmission of resistant bacteria in hospitals: Insights from an agent-based model
por: Almagor, Jonatan, et al.
Publicado: (2018)

Quantifying the extent of human disturbance activities and anthropogenic stressors in wetlands across the conterminous United States: results from the National Wetland Condition Assessment
por: Lomnicky, Gregg A., et al.
Publicado: (2019)

Rapid identification of capsulated Acinetobacter baumannii using a density-dependent gradient test
por: Kon, Hadas, et al.
Publicado: (2020)

Reliability, validity and normal ranges of the Zur Balance Scale for detecting mild postural control differences: introducing the modified, short version mZBS
por: Zur, Oz, et al.
Publicado: (2023)

Flexible Kernel Memory
por: Nowicki, Dimitri, et al.
Publicado: (2010)

Tissue microarrey: a potential cost-effective approach for mismatch repair testing in colorectal cancer
por: Farkash, Shai, et al.
Publicado: (2022)

Predictive models for type 2 diabetes onset in middle-aged subjects with the metabolic syndrome
por: Ozery-Flato, Michal, et al.
Publicado: (2013)

Laser tissue soldering of the gastrointestinal tract: A systematic review LTS of the gastrointestinal tract
por: Ashbell, Ido, et al.
Publicado: (2023)

Comparison of FOLFIRINOX vs Gemcitabine Plus Nab-Paclitaxel as First-Line Chemotherapy for Metastatic Pancreatic Ductal Adenocarcinoma
por: Klein-Brill, Avital, et al.
Publicado: (2022)

Term Idiopathic Polyhydramnios, and Labor Complications
por: Bas Lando, Maayan, et al.
Publicado: (2023)

Ectopic pancreatic pseudocyst and cyst presenting as a cervical and mediastinal mass - case report and review of the literature
por: Rokach, Ariel, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_2tqo7uthuguuab73l7bvuqu3o4