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Structure of promoter-bound TFIID and insight into human PIC assembly
The general transcription factor IID (TFIID) plays a central role in the initiation of RNA polymerase II-dependent transcription by nucleating pre-initiation complex (PIC) assembly at the core promoter. TFIID comprises the TATA-binding protein (TBP) and 13 TBP-associated factors (TAF1-13), which spe...
Autores principales: | Louder, Robert K., He, Yuan, López-Blanco, José Ramón, Fang, Jie, Chacón, Pablo, Nogales, Eva |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856295/ https://www.ncbi.nlm.nih.gov/pubmed/27007846 http://dx.doi.org/10.1038/nature17394 |
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