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Structure of promoter-bound TFIID and insight into human PIC assembly

The general transcription factor IID (TFIID) plays a central role in the initiation of RNA polymerase II-dependent transcription by nucleating pre-initiation complex (PIC) assembly at the core promoter. TFIID comprises the TATA-binding protein (TBP) and 13 TBP-associated factors (TAF1-13), which spe...

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Detalles Bibliográficos
Autores principales: Louder, Robert K., He, Yuan, López-Blanco, José Ramón, Fang, Jie, Chacón, Pablo, Nogales, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856295/
https://www.ncbi.nlm.nih.gov/pubmed/27007846
http://dx.doi.org/10.1038/nature17394

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